IMAGE. 1: microscopic picture of a -transplantable patient derived, entirely human- HAIROID™️ three-dimensional cell aggregate/ bioengineered hair-follicle in accordance with our IP disclosure.
We’ve filed an IP for the following technology:
METHODS FOR DERIVING AUTOLOGOUS AND HYPOIMMUNOGENIC HAIR FOLLICLE CONTAINING SHEETS IN VITRO
Abstract & technical field
The present IP disclosure relates to a bioengineering process to derive hair-follicles in vitro from the in vitro disposition and differentiation of pluripotent stem cells and dermal papilla cells. The present disclosure also relates to invitro bioengineering of hypoimmunogenic hair-follicles and hair-follicle containing sheets with asymmetric disposition of hair shafts and to reconstructing hair-follicle containing materials in vitro.
For our “IPSC merger technology” we use DNA free transfection methods [new IP in preparation] which prevents any kind of insertional mutagenesis because these vectors don’t integrate into the genome.
IMAGE. 2: microscopic picture of a - patient derived, entirely human- IPSC for the creation of the HAIROID™️ three-dimensional cell aggregate/ bioengineered hair-follicle in accordance with our IP disclosure.
IMAGE 3.: H&E staining confirming HF like properties in the early HAIROID prototype.